Published 2024-07-30
Keywords
- Charge transfer,
- Thermal analysis,
- Antibacterial,
- NMR
Copyright (c) 2024 Athul B.R, Venkatesh R, Vadivelan G (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
Abstract
A new charge transfer (CT) complex, Benzimidazol-3-ium furan-2-carboxylate (2FBI) was prepared and a method employed to purify solid compounds low temperature solution growth technique at comfortable temperature. The charge transfer compound was depicted using CHN analysis, Ultraviolet visible spectra, IR spectra, 1H NMR spectra, and thermal behavior. Thermogravimetric (TG) and differential thermal analysis are used to study its biological activities, including its antibacterial activity, which showed significant capacity against S. aureus and E. coli.
References
- D.K. Roy, A. Saha, A.K. Mukherjee, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 61(9) (2005) 2017-2022. https://doi.org/10.1016/j.saa.2004.08.001
- D.J. Brown, S.F. Mason, The Pyrimidines, Interscience Publishers, John Wiley & Sons, New York, 1962.
- S.M. Sondhi, M. Johar, S. Rajvanshi, S.G. Dastodar, R. Shukla, R. Raghubir, J.W. Lown, Anticancer, Anti-Inflammatory and Analgesic Activity Evaluation of Heterocyclic Compounds Synthesized by the Reaction of 4-Isothiocyanato-4-Methylpentan-2-One with Substituted o-Phenylenediamines, o-Diaminopyridine and (Un) Substituted o, Australian Journal of Chemistry, 54 (2001) 69-74. https://doi.org/10.1071/CH00141
- F.L. Zhao, B.Z. Xu, Z.Q. Zhang, S.Y. Tong, Study on the charge-transfer reaction between 7,7,8,8-tetracyanoquinodimethane and drugs, Journal of Pharmaceutical and Biomedical Analysis, 21(2) (1999) 355-360. https://doi.org/10.1016/S0731-7085(99)00121-1
- T. Murata, Y. Morita, K. Fuki, K. Sato, D. Shiomi, T. Takui, M. Maesato, H. Yamochi, G. Saito, K. Nakasuji, Murata, Y. Morita, K. Fuki, K. Sato, D. Shiomi, T. Takui, M. Maesato, H. Yamochi, G. Saito, K. Nakasuji, Angewandte Chemie International Edition. 43(46) (2004) 6343-6346. https://doi.org/10.1002/anie.200460801
- A.L. Sutton, B.F. Abrahams, D.M. D’Alessandro, R.W. Elliott, T.A. Hudson, R. Robson, P.M. Usov, Structural and optical investigations of charge transfer complexes involving the F4TCNQ dianion, CrystEngComm 16 (2014) 5234-5243. https://doi.org/10.1039/C4CE00289J
- Y. Li, D. Qi, P. Song, F. Ma, Fullerene-Based Photoactive Layers for Heterojunction Solar Cells: Structure, Absorption Spectra and Charge Transfer Process, Materials 8 (2015) 42-56. https://doi.org/10.3390/ma8010042
- V. Murugesan, M. Saravanabhavan, M. Sekar, Synthesis, characterization and pharmacological investigation of a new charge-transfer complex of 3-aminopyridinum-p-toluenesulfonate, Journal of Molecular Structure. 1084 (2015) 95-102. https://doi.org/10.1016/j.molstruc.2014.12.022
- V. Murugesan, M. Saravanabhavan, M. Sekar, Synthesis, spectral, structural analysis and biological evaluation of a new hydrogen-bonded charge-transfer complex: 2,3-Dimethylquinoxalinium-p-toluenesulfonate, Journal of Photochemistry and Photobiology B: Biology, 140 (2015) 20-27. https://doi.org/10.1016/j.jphotobiol.2014.07.003
- J.V. Greenhill & L. Lue, Progress in Medicinal Chemistry, vol. 30, (Eds. GP Ellis & DK Luscombe, Elsevier, New York), 1993, pp 170.
- P.N. Preston, Benzimidazoles, Chemistry of Heterocyclic Compounds: A Series Of Monographs, Part 1, Volume 40. https://doi.org/10.1002/9780470187159.ch1
- F. Touzeau, A. Arrault, G. Guillaumet, E. Scalbert, B. Pfeiffer, M.C. Rettori, P. Renard and J.Y. Merour, Synthesis and Biological Evaluation of New 2-(4,5-Dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine Derivatives, Journal of Medicinal Chemistry, 46 (2003) 1962-1979. https://doi.org/10.1021/jm021050c
- G. Vadivelan, M. Saravanabhavan, V. Murugesan, G. Gohulvani, M. Sekar & B. Babu, Synthesis, spectroscopic investigations, antioxidants and DNA binding studies of a charge transfer of benzimidazole with 4-methylbenzenesulfonic acid, Molecular Crystals and Liquid Crystals, 652 (2017) 242. https://doi.org/10.1080/15421406.2017.1378045
- G. Novitski, A. Borta, S. Shova, O. N. Kazheva, M. Gdaniec & Yu. A. Simonov, Russian Journal of Inorganic Chemistry, 53 (2008) 202-208. https://doi.org/10.1134/S0036023608020095
- A. Kololkovas, (1998) Essentials of Medicinal Chemistry, second ed., Wiley, New York.
- R. Mandal, S.C. Lahiri, Interactions of L-amino acids with metronidazole and tinidazole, Journal of the Indian Chemical Society, 76 (1999) 347-349.
- S.M. Andrade, S.M.B. Costa, R. Pansu, Structural Changes in W/O TRITON X-100/Cyclohexane-Hexanol/Water Microemulsions Probed by a Fluorescent Drug Piroxicam, Journal of Colloid and Interface Science, 226 (2000) 260-268. https://doi.org/10.1006/jcis.2000.6821
- K. Takahasi, K. Horino, T. Komura, K. Murata, Photovoltaic Properties of Porphyrin Thin Films Mixed with o-Chloranil, Bulletin of the Chemical Society of Japan, 3 (1993) 733-738. https://doi.org/10.1246/bcsj.66.733
- A. Eychmuller, A.I. Rogach, Chemistry and photophysics of thiol-stabilized II-VI semiconductor nanocrystals" Pure and Applied Chemistry. 72 (2000) 179-188. https://doi.org/10.1351/pac200072010179